The transport infrastructure in Zhitkovichi district is well-developed.
The majority of existing roads relate to the asphalt roads and the resurfaced roads. The road of international importance M1 and the roads of republican importance Р-23, Р-57, Р-88, Р-128 comprise the territory of Zhitkovichi district.
The rail service runs through the town of Zhitkovichi.
Zhitkovichi railway station is a way station with directions to Kalinkovichi and Luninets. Passenger trains connect it with Brest, Gomel, Grodno, Polotsk.
The nearest airports are situated in 248 km (Gomel) and 250 km (Minsk) away.